Why is Blaise short gut? Answer: Because a giant meconium cyst formed in her small bowel while she was in utero, causing the intestine to twist on itself and cut off its own blood supply.
Why did she have a giant cyst in her small bowel? Answer: Who knows?
Someday, Blaise is going to ask us why this all happened. It's an appropriate question for any kid with a chronic condition. Most of the time the answer is genes or environment. In utero meconium cysts are often caused by Cystic Fibrosis, a less-rare-than-you-think genetic disorder. We knew from prenatal screenings that I am not a carrier of the 100 most common CF mutations. We knew that Blaise also did not have any of those mutations and yesterday, we confirmed via a sweat test that Blaise does not have a rarer version of CF. We are Cystic Fibrosis free. Hooray for dodging a second diagnosis!
So now what? No CF. No malrotation. No known infection. Not, from what we can tell, genes. Not, from what we can tell, environment. Just bad luck. Not much of an answer, but there it is.